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Differentially Methylated Regions in Pediatric Multiple Sclerosis
An observational study analyzed DNA samples from 175 subjects (122 Pediatric MS patients and 53 healthy controls) and identified 55 differentially methylated regions (DMRs), with 28 affecting promoter regions. Notably, Epstein-Barr virus (EBV) infection emerged as a significant pathway in this context.
What this does not proveThe study establishes only associations without confirming causation and does not clarify the specific roles of each DMR in MS pathogenesis.