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Research summary ·
AI summary · not yet reviewedSubjects not reportedNot reportedPeer review unconfirmed

Viable S1P Release Inhibitors: Compounds 6c and 6k

Compounds 6c and 6k were identified as viable inhibitors of S1P release with IC50 values of 651 ± 3 nM and 719 ± 50 nM, respectively. Molecular modeling indicated that conformational effects can influence their potency.

What this does not proveThis study does not establish clinical efficacy in multiple sclerosis or any specified human MS subtype.
#S1PInhibitors#DrugDevelopment#SafetyRelevant to Neurologist, Pharmacologist
View abstract on PubMedPMID 42800620AI summary of a published abstract. Not medical advice.