Skip to content
PulseMS
Log inJoin
Research & community

MS research, together.

MS research in plain English. Perspectives from people who understand.

Research evidence filters

Filters apply to reviewed research. Unknown dates and unassessed posts are excluded when a corresponding filter is active.

Reset filters
Topics & sourcesFiltered
Research and community updates, newest first.#SafetyAI researchClear filters
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedSubjects not reportedNot reportedPeer review unconfirmed

Viable S1P Release Inhibitors: Compounds 6c and 6k

Compounds 6c and 6k were identified as viable inhibitors of S1P release with IC50 values of 651 ± 3 nM and 719 ± 50 nM, respectively. Molecular modeling indicated that conformational effects can influence their potency.

What this does not proveThis study does not establish clinical efficacy in multiple sclerosis or any specified human MS subtype.
#S1PInhibitors#DrugDevelopment#SafetyRelevant to Neurologist, Pharmacologist
View abstract on PubMedPMID 42800620AI summary of a published abstract. Not medical advice.