Erectile Dysfunction and Lower Urinary Tract Symptoms in Men with Multiple Sclerosis
In a study of 56 men with multiple sclerosis, 50% were found to have erectile dysfunction (ED), and 96.4% had lower urinary tract symptoms (LUTS). Strong correlations were noted between disability scores and ED and LUTS assessments, with erection confidence and urinary intermittency being particularly linked to disability severity.
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Why it matters
These findings highlight significant sexual and urinary health challenges faced by men with MS, emphasizing a need for further investigation into these issues.
What this does not prove
The study's findings are limited to men with MS, which may not represent the experiences of women or the general MS population.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Observational
- Participants / samples
- 56 · basis not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-02
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
Original sources
- Primary evidenceErectile dysfunction and lower urinary tract symptoms in men with multiple sclerosis. ↗DOI: 10.1055/s-0046-1829050
Supporting passages (9)
study designWe conducted a cross-sectional study enrolling 56 men with MS diagnosed through the McDonald criteria at the Reference Center for MS of the state of Paraíba, Brazil.
subjectsWe conducted a cross-sectional study enrolling 56 men with MS diagnosed through the McDonald criteria at the Reference Center for MS of the state of Paraíba, Brazil.
sample sizeCONCLUSION: Erectile dysfunction and LUTS were highly-prevalent in men with MS in the cohort of the present study.
findingsBACKGROUND: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system commonly associated with lower urinary tract symptoms (LUTS) and erectile dysfunction (ED); however, these conditions remain underinvestigated in Brazilian populations.
findingsBACKGROUND: Multiple sclerosis (MS) is a chronic demyelinating disease of the central nervous system commonly associated with lower urinary tract symptoms (LUTS) and erectile dysfunction (ED); however, these conditions remain underinvestigated in Brazilian populations.
findingsStrong correlations were found between the scores on the EDSS and the IIEF-5, the EDSS and the IPSS, and the IIEF-5 and the IPSS.
findingsThrough the analysis, we identified erection confidence and urinary intermittency as the subscale items most strongly associated with the EDSS score.
publication datePublication date: 2026-10-02
limitationsTitle: Erectile dysfunction and lower urinary tract symptoms in men with multiple sclerosis.
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