Effect of Occupational and Physiotherapy on Fatigue in MS Patients (Human Study)

subjects"eligibilityCriteria": "Inclusion Criteria:\n\n* Patients diagnosed with multiple sclerosis referred by the Neuroimmunology and Multiple Sclerosis Unit at Hospital Clínic de Barcelona who present symptoms of limiting fatigue.\n* Independence to perform basic activities of daily living.\n* Maximum EDSS score of 4.5.\n\nInclusion criteria for control group participants:\n\n* Patients who, despite meeting the inclusion criteria (6.1), are unable to attend the sessions (due to availability, geographic location, or other personal reasons) will be included in the comparison group.

sample size"count": 24

sample size basis"type": "ACTUAL"

randomized"allocation": "NON_RANDOMIZED"

controlled"type": "NO_INTERVENTION"

regulatory approval"isFdaRegulatedDrug": false

intervention"description": "Combination of Occupational Therapy and Physiotherapy strategies and sessions in-person, 2 days-week, during 12 months."

comparator"type": "NO_INTERVENTION"

primary endpoint"measure": "To determine the effectiveness of this program after completion (12 months after the start of the program) and at mid-term follow-up (18 months) in reducing the severity of perceived fatigue by the Modified Fatigue Impact Scale (MFIS)."

findingsOn the one hand, practicing different forms of physical exercise (PE) has demonstrated effective management of perceived fatigue, and the literature strongly supports the need for regular exercise in patients with MS.\n\nOn the other hand, energy conservation programs and cognitive-behavioral interventions have demonstrated improvements in self-efficacy, participation in social life, perceived control over their disease, and a reduction in the perceived impact of fatigue, particularly in the physical and psychosocial domains of life.\n\nTherefore, in this study, a physical therapist and an occupational therapist will conduct a one-year group program focused on educational and practical learning of techniques and strategies, keeping in mind that lifestyle changes take time to become permanent.\n\nIt is important to highlight that, as MS generally presents in early adulthood, there is growing interest in exploring rehabilitation techniques very early after diagnosis or in minimally affected MS patients (0-4.5 on the EDSS), we are therefore interested in exploring this program in this population group with MS, the majority of whom are actively employed, and evaluating the effects on perceived fatigue severity, quality of life, incidental and planned exercise, sleep quality, anxiety and depression, and perceived self-efficacy.\n\nStudy participants will be recruited by the neuroimmunology team at Hospital Clínic de Barcelona, who will select those who meet the inclusion criteria from the multiple sclerosis patients seen.

limitationsNo results are posted.