Effect of the Lexical Association Technique on Self-Esteem in MS Patients
The study is currently recruiting 160 participants with relapsing-remitting and secondary progressive multiple sclerosis to evaluate the effectiveness of the Lexical Association Technique (LAT) on self-esteem. Participants will be randomized into an experimental group using LAT and a control group performing similar tasks without direct self-reference. Self-esteem will be measured via the Rosenberg Self-Esteem Scale at multiple time points after the intervention.
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Why it matters
This research aims to explore new therapeutic techniques for improving self-esteem in individuals with multiple sclerosis, which may significantly impact their overall mental health and quality of life. Given that self-esteem can influence recovery and coping strategies, understanding these dynamics could lead to better supportive therapies.
What this does not prove
As the study is still in the recruitment phase, no results regarding the effectiveness of LAT have been published or are available for evaluation, and thus, it does not demonstrate any definitive findings yet.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- 160 · Estimated
- Randomised
- Yes
- Controlled
- Yes
- Primary endpoint met
- Not reported
- Relevant MS type
- RRMS, SPMS
- Publication date
- Not reported
- Evidence reviewed
- Trial registry record
- Regulatory approval
- No
- Research areas
- Other
Original sources
Supporting passages (14)
subjectsSelf-esteem will be measured at multiple time points (before, after, and up to 14 days after the intervention) to assess both immediate and lasting effects of the technique.\n\nPOPULATION The study will include two patient samples: one composed of patients recently diagnosed with RRMS, and another of patients recently diagnosed with SPMS.
sample size"count": 160
sample size basis"type": "ESTIMATED"
randomized"allocation": "RANDOMIZED"
controlled"interventionModel": "PARALLEL"
regulatory approval"isFdaRegulatedDrug": false
research categories"studyType": "INTERVENTIONAL"
relevant ms typesPsychiatric symptoms in patients with multiple sclerosis.
intervention"The Lexical Association Technique (LAT)"
comparatorThe 160 participants will be allocated using a minimization protocol into one of two groups: an experimental group using LAT and an active control group performing similar visualizations with no direct connection to the self.
primary endpoint"Effect of the therapeutic technique on patients' self-esteem assessed by comparing patients score at the RSES between the experimental and active control group after the procedure."
follow up"timeFrame": "To assess durability, self-esteem will be measured 3, 7, and 14 days (±2) after the end of the LAT or control procedure.
findingsTo achieve this, it relies on the repeated mental visualization of positive autobiographical episodes paired with positive self-referential linguistic statements.\n\nThe effectiveness of this technique in increasing self-esteem has been demonstrated and replicated across three studies, conducted with distinct samples: two involving healthy participants and one involving a clinical sample of individuals with a chronic illness (Niveau et al., 2022, 2023).",
limitationsTrial registry record. Publication date: unknown. No results are posted. Planned enrolment and endpoints are not findings.
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