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Research summary · AI summary · not yet reviewedHuman studyNot reportedTrial registry record – peer review not applicable
Study of Depression in Individuals with MS
A planned study involving 240 individuals with multiple sclerosis (MS) aims to evaluate depression levels using the Beck's Depression Inventory II. The study has not yet recruited participants and results are not available.
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This plain-English summary was written by AI from a trial registry record and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.
- Human efficacy
- Not yet assessed
- Mechanism
- Not yet assessed
- Evidence strength
- Not yet assessed
- Outcome
- Not yet assessed
Why it matters
This research is important because individuals with MS have high levels of depression, which is more pronounced than in other chronic illnesses. Understanding depression in this context could inform better support and interventions.
What this does not prove
No results are reported yet, and the planned enrolment and study endpoints do not constitute findings.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- 240 · basis not reported
- Randomised
- Yes
- Controlled
- Yes
- Primary endpoint met
- Not reported
- Relevant MS type
- All
- Publication date
- Not reported
- Evidence reviewed
- Trial registry record
- Regulatory approval
- No
- Research areas
- Other
Original sources
Supporting passages (11)
subjectsIndividuals with MS experience significantly high levels of depression which are higher than in any other chronic illness or neurological disorder.
sample size"count": 240, "type": "ESTIMATED"
randomized"allocation": "RANDOMIZED"
controlled"interventionModel": "PARALLEL"
regulatory approval"isFdaRegulatedDrug": false, "isFdaRegulatedDevice": false
research categories"Health and Wellbeing informational intervention"
relevant ms types"eligibilityCriteria": "Inclusion Criteria:\n\n* Aged 18 years or older\n* Clinical diagnosis of multiple sclerosis (MS)\n* Reports mild to moderate depressive symptoms, defined as a score of 14-28 on the Beck Depression Inventory-II (BDI-II)\n\nExclusion Criteria:\n\n* Gross cognitive impairment that would make participation in the eight online cognitive behavioural therapy (CBT) modules distressing or difficult\n* Inability to speak or read English\n* Acute organic brain syndrome (e.g., delirium)\n* A serious psychological disorder, including psychosis, bipolar disorder, or current substance use disorder, as determined by the Structured Clinical Interview for DSM-5 (SCID-5)\n* Severe depressive symptoms, defined as a BDI-II score of 29 or greater, as assessed using the BDI-II and SCID-5 Currently undertaking psychological treatment for depression and/or anxiety",
primary endpoint"measure": "Depression, measured on Beck's Depression Inventory II"
follow up"timeFrame": "Baseline, post intervention (8 weeks) and 28-weeks follow up"
findingsNo results are posted. Planned enrolment and endpoints are not findings.
limitationsNo results are posted. Planned enrolment and endpoints are not findings.
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