Higher Incidence of Diabetes in People with Multiple Sclerosis Compared to Matched Controls
Individuals with multiple sclerosis (MS) were found to have a 16% higher incidence of diabetes mellitus compared to matched controls. This diabetes was associated with increased hospitalisation rates and longer hospital stays, alongside a 41% higher mortality risk.
- Tags
- #MSResearch
- Most relevant to
- —
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Not graded
- Outcome
- Not reported
Why it matters
The findings suggest a significant link between MS and diabetes, highlighting an additional burden of health issues for people with MS. This raises awareness for better healthcare management in these patients.
What this does not prove
The study focused solely on individuals with MS and did not include those with pre-existing diabetes, limiting the generalizability of the results.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-20
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceIncident Comorbid Diabetes and Outcomes in Multiple Sclerosis: An English Population-Based Cohort Study. ↗DOI: 10.1002/acn3.70548
Supporting passages (7)
publication datePublication date: 2026-10-20
comparatorMETHODS: Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 controls without MS by age, sex and practice.
primary endpointINTERPRETATION: MS was associated with a higher incidence of diabetes mellitus, which was in turn associated with greater hospitalisation and mortality.
findingsAmong people with MS, incident diabetes mellitus was associated with higher hospitalisation rates (adjusted incidence rate ratio = 1.52, 1.42-1.64), longer hospitalisation duration (median 12 vs.
limitationsTitle: Incident Comorbid Diabetes and Outcomes in Multiple Sclerosis: An English Population-Based Cohort Study.
peer reviewedPublication types: Journal Article
subjectsMETHODS: Using English primary care data from the Clinical Practice Research Datalink, linked to hospital and mortality records, we matched adults with MS with up to 10 controls without MS by age, sex and practice.
AI assessment, not yet reviewed by a person · version 2 · Community votes are separate from evidence review.