Online Wellness Course and Exercise Platform for Progressive MS
A trial was planned to evaluate whether an online wellness program could reduce fatigue and improve quality of life in individuals aged 45-70 with progressive multiple sclerosis (MS). Participants, totaling 118, will be randomized into either the intervention group or a usual care control group, with follow-ups at 3 and 6 months. No results have been posted as the trial is not yet recruiting.
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Why it matters
This research aims to address significant disability, fatigue, and reduced quality of life associated with progressive forms of MS, potentially impacting many individuals.
What this does not prove
The trial is still in recruitment preparation, and no results or efficacy can be determined yet.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- 118 · Estimated
- Randomised
- Yes
- Controlled
- Yes
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- Not reported
- Evidence reviewed
- Trial registry record
- Regulatory approval
- No
- Research areas
- Not classified
Original sources
Supporting passages (12)
subjectsProgressive forms of the disease, including Primary Progressive Multiple Sclerosis (PPMS) and Secondary Progressive Multiple Sclerosis (SPMS), account for approximately 400,000 cases and are associated with substantial disability, fatigue, reduced quality of life, impaired mobility, mood disturbances, and cognitive challenges.
sample sizecount": 118, "type": "ESTIMATED"
sample size basistype": "ESTIMATED"
randomizedallocation": "RANDOMIZED"
controlledinterventionModelDescription": "Wait list control. The control group receives access to the online wellness course and the virtual exercise platform at the conclusion of the study."
regulatory approvalisFdaRegulatedDrug": false, "isFdaRegulatedDevice": false
interventionWellness online program and virtual exercise platform
comparatorContinues with usual care as directed by their neurologist
primary endpointThe Fatigue Severity Scale (FSS) is a 9-item patient-reported questionnaire that measures the impact and severity of fatigue on daily functioning.
follow upTopics include nutrition, stress management, and physical activity.\n* Have access to monthly group coaching calls by Zoom.\n* Have access to an online exercise platform.\n* Have access to email and text support from the study team.\n\nParticipants in the wait-list control group will:\n\n* Continue their usual diet, lifestyle, and medical care during the 6-month study period.\n* Complete the same study surveys as the intervention group.\n* Receive full access to the online wellness program, online exercise platform and support materials after completing their final 6-month surveys.\n\nAt the end of the study, all participants will complete final surveys about their symptoms, quality of life, and their experience with the program.
findings"briefSummary": "The goal of this clinical trial is to learn if an online wellness program can lower fatigue and improve mood and quality of life in people with progressive multiple sclerosis who are 45 to 70 years old and are experiencing significant fatigue disability.\n\nThe main questions it aims to answer are:\n\n* Does the online wellness program lower fatigue after 3 months and further lower fatigue after 6 months?\n* Does the online wellness program improve anxiety, depression, and quality of life after 3 months and lead to additional improvements after 6 months?
limitationsNo results are posted. Planned enrolment and endpoints are not findings.
AI assessment, not yet reviewed by a person · version 1 · Community votes are separate from evidence review.