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Research summary · AI summary · not yet reviewedHuman studyNot reportedTrial registry
Clinical Study on Pulmonary Lymphangioleiomyomatosis (LAM) in Humans
A study has been planned to enroll 2000 individuals with pulmonary lymphangioleiomyomatosis (LAM) to investigate the disease's clinical course and underlying cellular and molecular mechanisms using the Toshiba Aquilion One CT device.
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This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.
Why it matters
This research aims to gather important information about LAM, a rare progressive disease, which may lead to improved therapies.
What this does not prove
No results have been reported yet; the planned enrollment and endpoints currently do not provide any findings.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- Not reported
- Evidence reviewed
- Trial registry record
- Regulatory approval
- Not reported
- Research areas
- Not classified
Original sources
- Trial registrationStudy of the Disease Process of Lymphangioleiomyomatosis ↗
Supporting passages (6)
subjectsAllowing subjects to be included in the study may glean important information about individuals with uncommon pulmonary disease during and post pregnancy.\n\nRationale for inclusion of children (16 to \\< 18 years of age):\n\nLAM is a rare progressive disease that can manifest during adolescence, particularly in individuals with TSCassociated disease.
intervention"description": "The Toshiba Aquilion ONE CT system is currently being used for studies in both general CT radiology and CT cardiac imaging.
primary endpointThis study is designed to (a) define the clinical course of the disease and (b) elucidate the pathogenesis of the disease at the cellular and molecular levels, in order to develop more effective therapy.
follow upIf there is concern for abuse, coercion, exploitation, or danger, the study team will follow applicable mandatory reporting laws and institutional policies, including notification of appropriate authorities and/or a parent or guardian when required to protect the participant or as otherwise required.\n\nProcedures that will not be completed while the subject is pregnant and/or nursing include: Arterial Blood Gases (ABG), HIV testing, treadmill test, lung biopsy, thoracentesis, bronchoscopy, and measurements with imaging modalities requiring contrast or with radiation exposure such as Chest x-ray, CT scan, MRI with or without contrast, lung scan, bone densitometry (DEXA).
findingsNo results are posted. Planned enrolment and endpoints are not findings.
limitationsNo results are posted. Planned enrolment and endpoints are not findings.
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