Extracellular Vesicles in Neuroimmunologic Diseases: Insights from Human and Animal Studies
This systematic review discusses the potential of extracellular vesicles (EVs), particularly those derived from the central nervous system and found in peripheral blood, in the study of neuroimmunologic diseases.
- Tags
- #MSResearch
- Most relevant to
- —
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Moderate
- Outcome
- Not reported
Why it matters
Understanding the role of EVs could lead to advancements in research and clinical care for neuroimmunologic diseases, which are complex and not fully understood.
What this does not prove
The review points out significant gaps in knowledge regarding neuroimmunologic diseases and the challenges faced when integrating EV analysis into research and clinical practice.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Systematic review
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-21
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceThe Roles and Uses of Extracellular Vesicles in Neuroimmunologic Diseases. ↗DOI: 10.1523/jneurosci.2310-25.2026
Supporting passages (8)
study phaseHere, we discuss the potential of extracellular vesicles (EVs), especially CNS-derived EVs obtained from peripheral blood, as a promising avenue for advancing research and clinical care in neuroimmunology.
study designHere, we discuss the potential of extracellular vesicles (EVs), especially CNS-derived EVs obtained from peripheral blood, as a promising avenue for advancing research and clinical care in neuroimmunology.
subjectsHere, we discuss the potential of extracellular vesicles (EVs), especially CNS-derived EVs obtained from peripheral blood, as a promising avenue for advancing research and clinical care in neuroimmunology.
findingsHere, we discuss the potential of extracellular vesicles (EVs), especially CNS-derived EVs obtained from peripheral blood, as a promising avenue for advancing research and clinical care in neuroimmunology.
publication datePublication date: 2026-10-21
limitationsTitle: The Roles and Uses of Extracellular Vesicles in Neuroimmunologic Diseases.
peer reviewedPublication types: Journal Article; Review
subjectsMeSH terms: Humans; Animals; Extracellular Vesicles; Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease; Nervous System Diseases; Autoimmune Diseases of the Nervous System
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