Temperature Extremes and Autoimmune Diseases
Research indicates that temperature extremes due to climate change may significantly affect autoimmune conditions like multiple sclerosis (MS). Specifically, heat waves may exacerbate fatigue and neurological symptoms, while cold spells could lead to complications such as blood vessel constriction and tissue necrosis in other autoimmune diseases.
- Tags
- #MSResearch
- Most relevant to
- —
- Human efficacy
- Not yet assessed
- Mechanism
- Not yet assessed
- Evidence strength
- Not yet assessed
- Outcome
- Not yet assessed
Why it matters
Understanding the relationship between climate-induced temperature changes and autoimmune diseases like MS could help inform future public health strategies and patient care during extreme weather events.
What this does not prove
The study does not provide direct evidence from clinical trials on specific autoimmune diseases like MS; it discusses associations and mechanisms instead.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-13
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
Original sources
- Primary evidenceTemperature extremes and autoimmune diseases. ↗DOI: 10.1007/s00281-026-01089-6
Supporting passages (4)
publication date2026-10-13
findingsTemperature extremes present considerable specific health risk to people with autoimmune disease with examples including heat waves worsening fatigue and neurological symptoms in people with multiple sclerosis and cold spells triggering blood vessel constriction and extremity tissue necrosis in systemic sclerosis.
findingsTemperature extremes present considerable specific health risk to people with autoimmune disease with examples including heat waves worsening fatigue and neurological symptoms in people with multiple sclerosis and cold spells triggering blood vessel constriction and extremity tissue necrosis in systemic sclerosis.
limitationsTitle: Temperature extremes and autoimmune diseases.
AI assessment, not yet reviewed by a person · version 1 · Community votes are separate from evidence review.