Real-World Cadence Measurements in Black and White Adults with MS

In a study of 139 adults with multiple sclerosis (MS), Peak-30-minute cadence (Peak-30CAD) and peak 1-minute cadence (Peak-1CAD) were found to be significantly lower in Black participants compared to White participants, even after controlling for factors like age and disease duration.

Tags: #MSResearch
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Source: Read original source (PMID 42851006)

This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.

Why it matters

These findings suggest real-world mobility differences between racial groups in MS, which may be relevant for understanding walking performance and developing targeted interventions.

What this does not prove

The study does not establish causation between the measured cadence and walking performance, and it only provides a snapshot without assessing changes over time.

Next milestone

No next milestone was established from the available source.

Study facts

Study design: Observational
Participants / samples: 139 · basis not reported
Randomised: Not reported
Controlled: Not reported
Primary endpoint met: Yes
Relevant MS type: All
Publication date: 2026-10-08
Evidence reviewed: Abstract only
Regulatory approval: Not reported
Research areas: Not classified

Original sources

Primary evidenceReal-World, Device-Based Peak Cadence Metrics in Black and White Adults With Multiple Sclerosis. ↗DOI: 10.1177/15459683261493910

Supporting passages (11)

study designThe current study examined peak 30-minute cadence (Peak-30CAD) and peak 1-minute cadence (Peak-1CAD) in Black and White adults with MS.

subjectsMETHODS: Participants with MS who self-identified as Black (n = 43) or White (n = 96) completed the Timed 25-Foot Walk (T25FW) and 6-Minute Walk (6MW), and wore an accelerometer on a belt around the waist during the waking hours of the day for a 7-day period.

sample sizeMETHODS: Participants with MS who self-identified as Black (n = 43) or White (n = 96) completed the Timed 25-Foot Walk (T25FW) and 6-Minute Walk (6MW), and wore an accelerometer on a belt around the waist during the waking hours of the day for a 7-day period.

peer reviewedJournal: Neurorehabilitation and neural repair

primary endpoint metCONCLUSION: Peak-30CAD and Peak-1CAD were associated with laboratory-based walking performance in both Black and White adults with MS and may provide complementary real-world mobility metrics.

relevant ms typesBACKGROUND: Walking performance is worse in Black than White adults with multiple sclerosis (MS), and that difference might extend into real-world, device-based measurements.

publication datePublication date: 2026-10-08

primary endpointOBJECTIVE: The current study examined peak 30-minute cadence (Peak-30CAD) and peak 1-minute cadence (Peak-1CAD) in Black and White adults with MS.

follow upMETHODS: Participants with MS who self-identified as Black (n = 43) or White (n = 96) completed the Timed 25-Foot Walk (T25FW) and 6-Minute Walk (6MW), and wore an accelerometer on a belt around the waist during the waking hours of the day for a 7-day period.

findingsRESULTS: Peak-30CAD and Peak-1CAD along with T25FW and 6MW were significantly lower in Black than White participants when controlling for imbalances in age, sex, education, and disease duration, with the differences approaching a moderate magnitude.

limitationsTitle: Real-World, Device-Based Peak Cadence Metrics in Black and White Adults With Multiple Sclerosis.

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