Nutritional Status in Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease

In a cross-sectional study of 222 CNSIDD patients, 45.9% were at risk of or actively experiencing malnutrition. MS patients had lower mean Mini Nutritional Assessment scores compared to healthy controls. There was a significant correlation between nutritional status and quality of life metrics.

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Source: Read original source (PMID 42871865)

This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.

Human efficacy: Not yet assessed
Mechanism: Not yet assessed
Evidence strength: Not yet assessed
Outcome: Not yet assessed

Why it matters

Understanding malnutrition risks in CNSIDD patients can inform nutritional interventions and impact their quality of life. The relationship between nutritional status and disease characteristics is crucial for managing these conditions.

What this does not prove

The study does not establish causation between nutritional status and quality of life, and confounding factors related to treatment and comorbidities were not measured.

Next milestone

No next milestone was established from the available source.

Study facts

Study design: Observational
Participants / samples: 222 · Total CNSIDD patients included in the study
Randomised: Not reported
Controlled: Yes
Primary endpoint met: Not reported
Relevant MS type: Not reported
Publication date: 2026-09-26
Evidence reviewed: Abstract only
Regulatory approval: Not reported
Research areas: Other

Original sources

Primary evidenceNutritional Status in Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease. ↗DOI: 10.14740/jocmr6676

Supporting passages (9)

study designMETHODS: A cross-sectional study at Siriraj Hospital included patients with CNSIDD aged > 18 years and matched healthy controls (HCs).

subjectsRESULTS: The study included 222 patients (100 multiple sclerosis (MS), 105 neuromyelitis optica spectrum disorder (NMOSD), and 17 myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)) with a mean age of 46.2 years (standard deviation (SD) 15.2).

sample sizeRESULTS: The study included 222 patients (100 multiple sclerosis (MS), 105 neuromyelitis optica spectrum disorder (NMOSD), and 17 myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)) with a mean age of 46.2 years (standard deviation (SD) 15.2).

sample size basisRESULTS: The study included 222 patients (100 multiple sclerosis (MS), 105 neuromyelitis optica spectrum disorder (NMOSD), and 17 myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD)) with a mean age of 46.2 years (standard deviation (SD) 15.2).

controlledMETHODS: A cross-sectional study at Siriraj Hospital included patients with CNSIDD aged > 18 years and matched healthy controls (HCs).

research categoriesRoutine nutritional screening is an essential component of standard care for this population.

findingsOverall, 102/222 (45.9%) CNSIDD patients were at risk of or actively experiencing malnutrition.

publication datePublication date: 2026-09-26

limitationsTitle: Nutritional Status in Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorder, and Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease.

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