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Research summary · 3 d ago

AI summary · not yet reviewedHuman studyNot reportedPublished in a peer-reviewed journal

Human Study on Sleep Quality, Dysfunctional Beliefs, and Quality of Life in Multiple Sclerosis

In a study of 200 people with multiple sclerosis, worse self-reported sleep quality and more dysfunctional sleep beliefs were linked to poorer physical and mental health outcomes. Dysfunctional beliefs played a mediating role between sleep quality and mental health scores, with notable interactions involving demographics and clinical factors.

Tags: #MSResearch
Most relevant to: —
Source: Read original source (PMID 42903014)

This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.

Human efficacy: Not established from this source
Mechanism: Not reported
Evidence strength: Not graded
Outcome: Not reported

Why it matters

These findings highlight the importance of sleep quality and beliefs about sleep on the overall health-related quality of life for people with multiple sclerosis.

What this does not prove

Causal relationships cannot be established due to the cross-sectional nature of the study and reliance on self-reported measures, which may not reflect all elements of sleep and quality of life.

Next milestone

No next milestone was established from the available source.

Study facts

Study design: Not reported
Participants / samples: 200 · Participants (N = 200) completed the Pittsburgh Sleep Quality Index (PSQI), the Dysfunctional Beliefs and Attitudes about Sleep Scale-16 (DBAS-16), and HRQOL/F patient-reported outcome measures (PROMs).
Randomised: Not reported
Controlled: Not reported
Primary endpoint met: Not reported
Relevant MS type: All
Publication date: 2025-09-29
Evidence reviewed: Abstract only
Regulatory approval: Not reported
Research areas: Not classified
Biological target: Not reported
Pathway: Not reported
Population: Not reported
Size of effect: Not reported
Secondary endpoints: Not reported
MRI endpoints: Not reported
Biomarkers: Not reported
Safety: Not reported

Original sources

Primary evidenceSleep Quality, Dysfunctional Sleep Beliefs, and Health-Related Quality of Life and Functioning in People With Multiple Sclerosis. ↗DOI: 10.7224/1537-2073.2024-050

Supporting passages (8)

peer reviewedPublication types: Journal Article

sample size200

sample size basisParticipants (N = 200) completed the Pittsburgh Sleep Quality Index (PSQI), the Dysfunctional Beliefs and Attitudes about Sleep Scale-16 (DBAS-16), and HRQOL/F patient-reported outcome measures (PROMs).

relevant ms typesAll

publication date2025-09-29

findingsRESULTS: Worse self-reported sleep quality and a greater degree of dysfunctional sleep beliefs were significantly associated with worse t scores for global HRQOL/F physical and mental health outcomes and several Quality of Life in Neurological Disorders (Neuro-QoL) scales. Dysfunctional sleep beliefs significantly mediated the association between PSQI and HRQOL/F mental health outcomes and several Neuro-QoL scales, and significant interactions between PSQI, DBAS-16, and demographic/clinical factors were revealed.

limitationsTitle: Sleep Quality, Dysfunctional Sleep Beliefs, and Health-Related Quality of Life and Functioning in People With Multiple Sclerosis.

subjectsTitle: Sleep Quality, Dysfunctional Sleep Beliefs, and Health-Related Quality of Life and Functioning in People With Multiple Sclerosis.

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