Systematic Review on Susceptibility-Weighted Imaging (SWI) in Brain MRI for Multiple Sclerosis and Other Conditions
A systematic review recommends including susceptibility-weighted imaging (SWI) in brain MRI protocols for diagnosing conditions like cerebral amyloid angiopathy and monitoring therapies, particularly addressing their relevance in multiple sclerosis.
- Tags
- #MSResearch
- Most relevant to
- —
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Moderate
- Outcome
- Not reported
Why it matters
Incorporating SWI may enhance the diagnostic accuracy and management of various neurological conditions by revealing critical vascular and microvascular changes not visible with standard imaging.
What this does not prove
These recommendations are based on moderate to high evidence for specific conditions but do not encompass all possible scenarios for SWI application.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Systematic review
- Participants / samples
- Not reported
- Randomised
- Not applicable
- Controlled
- Not applicable
- Primary endpoint met
- Not applicable
- Relevant MS type
- Not reported
- Publication date
- 2026-10-31
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceESR Essentials: susceptibility-weighted imaging-practice recommendations by the European Society for Magnetic Resonance in Medicine and Biology. ↗DOI: 10.1007/s00330-026-12988-5
Supporting passages (10)
study designPublication types: Journal Article; Review
subjectsESR Essentials: susceptibility-weighted imaging-practice recommendations by the European Society for Magnetic Resonance in Medicine and Biology.
findingsSWI should be included in brain MRI protocols when haemorrhagic or microvascular susceptibility findings are expected to affect diagnosis or management, especially in cerebral amyloid angiopathy, anti-amyloid therapy monitoring, traumatic brain injury, and neuro-oncology or multiple sclerosis work-up.
limitationsOverall, these constitute the core recommended brain scenarios for SWI supported by moderate to high levels of evidence.
publication datePublication date: 2026-10-31
peer reviewedPublication types: Journal Article; Review
study phasePublication types: Journal Article; Review
randomizedPublication types: Journal Article; Review
controlledPublication types: Journal Article; Review
primary endpoint metPublication types: Journal Article; Review
AI assessment, not yet reviewed by a person · version 1 · Community votes are separate from evidence review.