Fatigue, Depressive Symptoms, and Mediterranean Diet Adherence Among Adults with Multiple Sclerosis

In a study involving 112 adults with multiple sclerosis, 92% reported clinically significant fatigue, while 89.9% were at high risk for depressive symptoms. The study found that 51.8% of participants had low adherence to the Mediterranean diet, and lower adherence was associated with greater fatigue severity. Additionally, there was a strong correlation between fatigue severity and depressive symptoms.

Tags: #MSResearch
Most relevant to: —
Source: Read original source (PMID 42801458)

This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.

Why it matters

These findings highlight a potential link between diet adherence and mental health in individuals with multiple sclerosis, emphasizing the importance of lifestyle factors in managing fatigue and depressive symptoms.

What this does not prove

The study's cross-sectional design limits the ability to infer causation, and the sample size may restrict the generalizability of the results.

Next milestone

No next milestone was established from the available source.

Study facts

Study design: Observational
Participants / samples: Not reported
Randomised: Not reported
Controlled: Not reported
Primary endpoint met: Not reported
Relevant MS type: Not reported
Publication date: 2026-09-27
Evidence reviewed: Abstract only
Regulatory approval: Not reported
Research areas: Not classified

Original sources

Primary evidenceFatigue, depressive symptoms, and Mediterranean diet adherence among Greek adults with multiple sclerosis. ↗DOI: 10.1080/13548506.2026.2736866

Supporting passages (6)

study designThis cross-sectional study aimed to examine fatigue and depressive symptoms in adults with MS and explore their associations with adherence to the Mediterranean diet and individual dietary components.

subjectsA total of 112 adults with MS (mean age 45.26 ± 9.9 years) were included.

publication date2026-09-27

primary endpointThis cross-sectional study aimed to examine fatigue and depressive symptoms in adults with MS and explore their associations with adherence to the Mediterranean diet and individual dietary components.

findingsClinically significant fatigue (FSS ≥ 4) was present in 92.0%, while 89.9% were at high risk for depressive symptoms (CES-D ≥ 16).

limitationsTitle: Fatigue, depressive symptoms, and Mediterranean diet adherence among Greek adults with multiple sclerosis.

AI assessment, not yet reviewed by a person · version 1 · Community votes are separate from evidence review.