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Research summary · AI summary · not yet reviewedHuman studyNot reportedPublished in a peer-reviewed journal
Nutraceutical Supplementation in Patients with Autoimmune Diseases
A systematic review of 30 clinical trials involving 2,107 participants with autoimmune diseases found that supplementation with various nutraceuticals like curcumin and probiotics resulted in anti-inflammatory effects, improved disease activity, and decreased autoantibody levels.
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This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Not graded
- Outcome
- Not reported
Why it matters
These findings suggest that nutraceuticals may potentially influence autoimmune disease management, highlighting the need for further specific research in MS.
What this does not prove
The review does not establish the specific efficacy of individual nutraceuticals for MS due to insufficient focused studies on this condition.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- 2107 · Thirty clinical trials involved 2,107 participants with rheumatoid arthritis, psoriasis, multiple sclerosis, systemic lupus erythematosus, or Hashimoto's thyroiditis.
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-08-16
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceEfficacy of nutraceuticals as adjunctive therapies in autoimmune diseases: A systematic review of clinical trials. ↗DOI: 10.34172/bi.33535
Supporting passages (9)
sample sizeThirty clinical trials involved 2,107 participants with rheumatoid arthritis, psoriasis, multiple sclerosis, systemic lupus erythematosus, or Hashimoto's thyroiditis.
sample size basisThirty clinical trials involved 2,107 participants with rheumatoid arthritis, psoriasis, multiple sclerosis, systemic lupus erythematosus, or Hashimoto's thyroiditis.
publication date2026-08-16
interventionnutraceutical supplementation
findingsThe studies demonstrated anti-inflammatory and immunoregulatory effects, as well as improvements in disease activity and clinical symptoms following supplementation with curcumin, probiotics, vitamin D, omega-3 fatty acids, baicalin, resveratrol, and quercetin.
findingsAdditionally, reductions in autoantibody levels were observed after supplementation with curcumin, selenium, and genistein.
limitationsTitle: Efficacy of nutraceuticals as adjunctive therapies in autoimmune diseases: A systematic review of clinical trials.
peer reviewedPublication types: Journal Article; Review
subjectsMETHODS: A comprehensive search was conducted on PubMed, Embase, and ClinicalTrials.gov to identify studies published between 2010 and 2025 evaluating nutraceutical supplementation in patients with autoimmune diseases.
AI assessment, not yet reviewed by a person · version 2 · Community votes are separate from evidence review.