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Research summary · AI summary · not yet reviewedHuman studyObservationalTrial registry
Electrical Stimulation in Pediatric Drug-Refractory Epilepsy (DRE)
The study is currently evaluating the safety, tolerability, yield, and validity of Electrical Stimulation for Seizure Induction (ESIS) in pediatric patients with DRE. No results are available as the study is active and not recruiting participants.
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This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.
Why it matters
This research aims to enhance the identification of the epileptogenic zone in pediatric DRE patients, which could improve surgical candidacy and outcomes for those with complex epilepsy.
What this does not prove
Currently, no results have been published, and endpoints are not disclosed. Details about study findings are yet to be reported.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Observational
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- Not reported
- Evidence reviewed
- Trial registry record
- Regulatory approval
- Not reported
- Research areas
- Not classified
Original sources
- Trial registrationESIS in Pediatric DRE ↗
Supporting passages (7)
study phaseThis study differs from routine clinical care in that all study patients will undergo electrical stimulation in all or nearly all electrode contacts.
study designDespite these promising reports, ESIS is not widely integrated into pediatric DRE evaluation.\n\nThe overall objective is to improve methods of EZ identification in pediatric DRE patients with complex EZs, thereby increasing the likelihood of surgical candidacy for patients and ultimately improving surgical outcomes.
subjectsParticipants with drug-refractory epilepsy who receive care at or are referred into the CCHMC Comprehensive Epilepsy Center will comprise the targeted study population.
intervention"officialTitle": "Electrical Stimulation for Seizure Induction in Pediatric Drug-Refractory Epilepsy (ESIS in Pedriatric DRE)."
primary endpointEvaluate the safety of ESIS in pediatric DRE patients.
findingsSo far, there is not as much published data on seizure stimulation for pediatric patients.\n\nThis research study thus has the potential both to help individual patients (by providing specific information about your seizure networks) and to help pediatric patients with epilepsy in general (by increasing our understanding of stimulated seizures in children, teenagers and young adults).",
limitationsTrial registry record. Publication date: unknown. No results are posted. Planned enrolment and endpoints are not findings.
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