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Research summary · AI summary · not yet reviewedHuman studyNot reportedPublished in a peer-reviewed journal
1RM-Based Protocol for Maximum Inspiratory and Expiratory Pressures Tests in Individuals with Multiple Sclerosis
A study validated a new 1RM-based protocol for measuring maximum inspiratory (MIP) and expiratory pressures (MEP) in 52 individuals with multiple sclerosis. The protocol showed good to excellent concurrent validity and test-retest reliability when compared to a digital manometer reference test.
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This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Not graded
- Outcome
- Not reported
Why it matters
This research provides evidence for a reliable method to assess respiratory function in multiple sclerosis patients, which is important for clinical evaluations and potential interventions.
What this does not prove
The study only assessed the validity and reliability of the protocol and did not evaluate its impact on clinical outcomes.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-20
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceA New Protocol for Evaluating Maximum Respiratory Pressures in Individuals With Multiple Sclerosis: Concurrent Validity and Test-Retest Reliability. ↗DOI: 10.1097/npt.0000000000000586
Supporting passages (10)
sample size basisFifty-two individuals (53.6 ± 10 years; 5.7 ± 1.8 points on Expanded Disability Status Scale) (46% relapsing-remitting; 23% primary progressive; 31% secondary progressive)
publication date2026-10-20
interventionDISCUSSION AND CONCLUSION: This study validated a new 1RM-based protocol for the MIP/MEP tests using a respiratory muscle training threshold valve device in individuals with multiple sclerosis, showing good to excellent concurrent validity compared with the reference test, as well as good to excellent test-retest reliability.
comparatorMIP/MEP tests were performed using a threshold valve device (1RM-based protocol) and a digital manometer (reference test).
primary endpointDISCUSSION AND CONCLUSION: This study validated a new 1RM-based protocol for the MIP/MEP tests using a respiratory muscle training threshold valve device in individuals with multiple sclerosis, showing good to excellent concurrent validity compared with the reference test, as well as good to excellent test-retest reliability.
follow uptwo appointments 7 to 10 days apart
findingsDISCUSSION AND CONCLUSION: This study validated a new 1RM-based protocol for the MIP/MEP tests using a respiratory muscle training threshold valve device in individuals with multiple sclerosis, showing good to excellent concurrent validity compared with the reference test, as well as good to excellent test-retest reliability.
limitationsTitle: A New Protocol for Evaluating Maximum Respiratory Pressures in Individuals With Multiple Sclerosis: Concurrent Validity and Test-Retest Reliability.
peer reviewedPublication types: Journal Article
subjectsTitle: A New Protocol for Evaluating Maximum Respiratory Pressures in Individuals With Multiple Sclerosis: Concurrent Validity and Test-Retest Reliability.
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