Observational Study of People with Multiple Sclerosis
The study reviewed chart data from 455 individuals with multiple sclerosis (PwMS) to identify characteristics linked to meeting Canadian physical activity guidelines (PAGs). Findings showed that PwMS who do not drive, are non-ambulatory, have higher disability scores, use gait aids, experience incoordination, have progressive MS, or smoke have lower odds of engaging in aerobic activities.
- Tags
- #MSResearch
- Most relevant to
- —
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Limited
- Outcome
- Not reported
Why it matters
These findings highlight specific barriers faced by PwMS in achieving recommended physical activity levels, which is vital for their health and quality of life.
What this does not prove
The study's retrospective nature may introduce biases and the sample might not reflect all PwMS, as it was drawn from a single tertiary clinic.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Observational
- Participants / samples
- 455 · basis not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-21
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- People with multiple sclerosis referred to physiatry at a Canadian tertiary MS clinic
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceWhat characteristics are associated with meeting the Canadian physical activity guidelines for people with multiple sclerosis? A retrospective chart review. ↗DOI: 10.1139/apnm-2026-0050
Supporting passages (9)
study designThis study aimed to examine which sociodemographic and clinical characteristics are associated with meeting the Canadian MS PAGs.
subjectsThis study aimed to examine which sociodemographic and clinical characteristics are associated with meeting the Canadian MS PAGs.
sample sizeA retrospective chart review of all PwMS referred to physiatry at the largest Canadian tertiary MS clinic between December 2021-December 2023 (n=455) was conducted.
primary endpointA retrospective chart review of all PwMS referred to physiatry at the largest Canadian tertiary MS clinic between December 2021-December 2023 (n=455) was conducted.
findingsHigher Expanded Disability Status Scale (OR=0.80, 95% CI=0.70-0.91), gait aid use (OR=0.55, 95%CI=0.34-0.88), incoordination (OR= 0.52, 95% CI=0.33-0.82), progressive MS phenotype (OR=0.60, 95% CI=0.37-0.95), and smoking (OR=0.31, 95% CI=0.13-0.76) were associated with lower odds of doing any aerobic activity.
populationA retrospective chart review of all PwMS referred to physiatry at the largest Canadian tertiary MS clinic between December 2021-December 2023 (n=455) was conducted.
publication datePublication date: 2026-10-21
limitationsTitle: What characteristics are associated with meeting the Canadian physical activity guidelines for people with multiple sclerosis? A retrospective chart review.
peer reviewedPublication types: Journal Article
AI assessment, not yet reviewed by a person · version 1 · Community votes are separate from evidence review.