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Research summary · AI summary · not yet reviewedHuman studySystematic reviewPublished in a peer-reviewed journal
Human Subjects: Theory-Based Nursing Interventions for Multiple Sclerosis
A systematic review of nine randomized controlled trials found that theory-based nursing interventions were linked to significant improvements in quality of life, self-efficacy, daily living activities, and other health outcomes for individuals with multiple sclerosis.
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This plain-English summary was written by AI from a published abstract and may contain errors. It is not medical advice. Read the original study and talk to your MS team before making decisions about treatment.
- Human efficacy
- Demonstrated in people
- Mechanism
- Not reported
- Evidence strength
- Moderate
- Outcome
- Not reported
Why it matters
These findings suggest that structured nursing interventions can effectively support patients with multiple sclerosis, enhancing their overall health and well-being.
What this does not prove
The study limited its review to a small number of eligible RCTs, which may affect the generalizability of the results.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Systematic review
- Participants / samples
- 9 · basis not reported
- Randomised
- Yes
- Controlled
- Yes
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-11
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceExamining the effectiveness of theory-based nursing interventions for patients with multiple sclerosis (MS): A systematic review of randomized controlled trials. ↗DOI: 10.1016/j.msard.2026.107957
Supporting passages (11)
study designThe aim of this systematic review was to evaluate the effectiveness of theory-based nursing interventions for individuals with multiple sclerosis (MS).
subjectsthe application of these theory-based nursing interventions were associated with statistically significant improvements across multiple outcomes, including quality of life, self-efficacy, activities of daily living, treatment adherence, hope, fatigue, stress regulation, lifestyle modification, and sleep quality.
sample sizeFollowing a rigorous screening process in accordance with the PRISMA guidelines, nine studies meeting the predefined eligibility criteria were included in the review.
randomizedRESULTS: The included studies evaluated interventions grounded in nursing theories, including Orem's Self-Care Model (n = 3), the Continuous Care Model (n = 3), Pender's Health Promotion Model (n = 1), the Theory of Goal Attainment (n = 1), and the Collaborative Care Model (n = 1).
controlledThe findings indicate that the application of these theory-based nursing interventions were associated with statistically significant improvements across multiple outcomes, including quality of life, self-efficacy, activities of daily living, treatment adherence, hope, fatigue, stress regulation, lifestyle modification, and sleep quality.
peer reviewedMultiple sclerosis and related disorders
findingsThe findings indicate that the application of these theory-based nursing interventions were associated with statistically significant improvements across multiple outcomes, including quality of life, self-efficacy, activities of daily living, treatment adherence, hope, fatigue, stress regulation, lifestyle modification, and sleep quality.
human efficacyCONCLUSION: Theory-based nursing interventions not only yield significant positive effects on physical, psychological, and behavioral outcomes among individuals with multiple sclerosis but also serve as an essential framework for guiding the planning and delivery of holistic nursing care.
publication datePublication date: 2026-10-11
limitationsTitle: Examining the effectiveness of theory-based nursing interventions for patients with multiple sclerosis (MS): A systematic review of randomized controlled trials.
peer reviewedPublication types: Journal Article; Review
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