Review of Neuroinflammatory and Demyelinating Disorders in Children
This review provides an updated clinico-radiological summary of pediatric-onset multiple sclerosis (POMS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD).
- Tags
- #MSResearch
- Most relevant to
- —
- Human efficacy
- Not established from this source
- Mechanism
- Not reported
- Evidence strength
- Not graded
- Outcome
- Not reported
Why it matters
The review emphasizes the importance of MRI protocols and advanced sequences for detecting lesions and differentiating phenotypes in these disorders, providing valuable insights for researchers and clinicians.
What this does not prove
The review does not establish clinical efficacy outcomes or provide new treatment results.
Next milestone
No next milestone was established from the available source.
Study facts
- Study design
- Not reported
- Participants / samples
- Not reported
- Randomised
- Not reported
- Controlled
- Not reported
- Primary endpoint met
- Not reported
- Relevant MS type
- Not reported
- Publication date
- 2026-10-24
- Evidence reviewed
- Abstract only
- Regulatory approval
- Not reported
- Research areas
- Not classified
- Biological target
- Not reported
- Pathway
- Not reported
- Population
- Not reported
- Size of effect
- Not reported
- Secondary endpoints
- Not reported
- MRI endpoints
- Not reported
- Biomarkers
- Not reported
- Safety
- Not reported
Original sources
- Primary evidenceNeuroinflammatory and demyelinating disorders in children: demystifying and updating with a focus on myelin oligodendrocyte glycoprotein antibody-associated disease. ↗DOI: 10.1007/s00247-026-06800-1
Supporting passages (4)
publication date2026-10-24
findingsThis review provides an up-to-date clinico-radiological summary of pediatric-onset multiple sclerosis (POMS), neuromyelitis optica spectrum disorder (NMOSD), and myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD), emphasizing MRI protocols and advanced sequences for lesion detection and phenotypic differentiation.
limitationsTitle: Neuroinflammatory and demyelinating disorders in children: demystifying and updating with a focus on myelin oligodendrocyte glycoprotein antibody-associated disease.
peer reviewedPublication types: Journal Article; Review
AI assessment, not yet reviewed by a person · version 1 · Community votes are separate from evidence review.