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Human Subjects Research on Serum GFAP and Age in NMOSD Diagnosis
In a study of 640 patients, serum GFAP levels and age effectively differentiated various neuromyelitis optica spectrum disorders (NMOSD), particularly AQP4-NMOSD, from other conditions like MOGAD. The study found high diagnostic accuracy measured by area under the curve (AUC), indicating strong potential for these biomarkers in clinical diagnosis.
What this does not proveThe findings are limited to differentiating NMOSD from other diseases and do not reflect treatment efficacy or direct clinical outcomes.