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AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyObservationalPeer review unconfirmed

Long-term Disability Trends in Multiple Sclerosis: Observational Study of Human Patients

In a 10-year study involving 391 self-enrolled MS patients in the Netherlands, disabilities related to daily activities increased over time, while some aspects of disability related to environmental support improved. Other disabilities remained stable, and QoL scores showed no change.

What this does not proveThe study does not establish causation or the impact of interventions and may be subject to selection bias due to its self-enrolled cohort.
#SymptomMgmt#Wellness#HealthcareSupport#QualityOfLifeRelevant to Neurologist, HealthcarePolicy
View abstract on PubMedPMID 42799509AI summary of a published abstract. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedSubjects not reportedInterventionalPeer-reviewed

Effects of Mixed-Amphetamine Salts on Cognitive Function in MS Model

In a randomized, controlled study of 123 participants with MS over 12 weeks, no significant differences were found in cognitive function as measured by the Symbol Digit Modalities Test (SDMT) between those receiving mixed-amphetamine salts (MAS-XR) and a placebo (p = 0.545). There were significant differences in psychosocial measures for the 20 mg MAS-XR group compared to placebo (p = 0.041).

What this does not proveThe study did not show that MAS-XR is effective for cognitive impairment in MS, and the age mismatch between groups could impact the results.
#CognitiveImpairment#Fatigue#QualityOfLife#SymptomMgmtRelevant to Neurologist, Psychiatrist
View abstract on PubMedPMID 42800227AI summary of a published abstract. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyPhase 2Peer-reviewed

Telehealth Self-Management Educational Program in People with Multiple Sclerosis

In a study of 42 people with multiple sclerosis (PwMS), a telehealth self-management educational program led to significant improvement in quality of life, as shown by increased scores on the Multiple Sclerosis Self-Management Scale-Revised (MSSM-R) and the Multiple Sclerosis International Quality of Life (MusiQoL) questionnaire from baseline to 3 months (p < 0.001).

What this does not proveThe study's design lacks a control group and randomization, which limits the strength of its conclusions regarding the efficacy of the intervention.
#Telehealth#SelfManagement#QualityOfLife#WellnessRelevant to Neurologist, Physical Therapist
View abstract on PubMedPMID 42789209AI summary of a published abstract. Not medical advice.