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MS clinical trials

Records classified as trial registrations. A registry entry describes a study record; it does not by itself establish that a treatment works or that a trial has reported results.

This hub updates as matching research records are published. AI-generated summaries are labelled when they have not yet been reviewed by a person.

AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyInterventionalTrial registry record – peer review not applicable

Interventional Study of StableEyes in Human Subjects

A study involving 138 human participants aimed to evaluate the effect of an intervention called StableEyes. The primary outcome was to measure Composite VOR gain (cVOR gain). However, no results have been posted, and planned enrollment and endpoints were not reported as findings.

What this does not proveThe study lacks posted results, making it impossible to assess outcomes or scientific validity; planned enrollment and endpoints do not provide evidence of effectiveness or safety.
View trial record on ClinicalTrials.govNCT06495138AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyInterventionalTrial registry record – peer review not applicable

Tai Chi Training in People with Relapsing-Remitting MS (RRMS)

A trial planned to evaluate the effects of Tai Chi training on individuals with RRMS involved an estimated 35 participants, assessing physical and psychological impacts over 12 weeks. However, no results have been posted, and the planned enrollment has no evidential basis yet.

What this does not proveThere are no results available from the trial, and the estimated enrollment does not provide any conclusive findings on efficacy or safety.
View trial record on ClinicalTrials.govNCT07890974AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyInterventionalTrial registry record – peer review not applicable

SPIN Exercise-Training in Human Subjects

A study with 100 planned participants aimed to assess changes in physical activity levels and strength training between SPIN exercise-training and a control group following a wellness program. The primary endpoints included self-reported weekly minutes of moderate-to-vigorous physical activity and strength training metrics. However, no results or findings have been posted yet.

What this does not proveNo results are posted, meaning we cannot assess the study's outcomes or effectiveness, leaving the findings and impacts unknown.
View trial record on ClinicalTrials.govNCT07891520AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyInterventionalTrial registry record – peer review not applicable

Diffusion-Weighted MRI in Multiple Sclerosis: A Study with Human Subjects

A study involving 50 human participants with multiple sclerosis used diffusion-weighted magnetic resonance imaging to measure IVIM parameters like ADC, D, D*, and f in brain regions. However, no results have been posted yet, and the endpoints planned for the study remain unreported.

What this does not proveThe lack of results means we can't draw any conclusions about the intervention's effectiveness or impact on patients. Planned enrollment and endpoints are not findings themselves.
View trial record on ClinicalTrials.govNCT05391906AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyPhase 3Trial registry record – peer review not applicable

Phase 3 Study on Rapamycin for Drug-Resistant Epilepsy in Patients with Tuberous Sclerosis Complex

A Phase 3 interventional study planned to enroll 200 patients aged 3 months to 50 years with drug-resistant epilepsy related to Tuberous Sclerosis Complex (TSC). The study aimed to compare seizure reduction between rapamycin and placebo groups, as well as assess adverse events. However, no results have been published yet.

What this does not proveNo results are posted; therefore, efficacy and safety outcomes have not been established, leaving the study's impact unknown.
View trial record on ClinicalTrials.govNCT05534672AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyObservationalTrial registry record – peer review not applicable

Observational Study in Human Participants on EDSS Change

An observational study planned to enroll 120 participants to assess changes in Expanded Disability Status Scale (EDSS) over 18 months using a composite severity score. However, no results have been posted to date, and the publication date is unknown.

What this does not proveThe study has not reported any results, making it impossible to assess its findings or implications. The publication date is also unknown.
View trial record on ClinicalTrials.govNCT03369106AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyInterventionalTrial registry record – peer review not applicable

OPM-Magnetoencephalography Research in Children with Immune-Mediated Neurological Diseases

A study was planned to enroll 90 children aged 2 to 16 diagnosed with immune-mediated neurological diseases. The aim was to detect differences in brain imaging metrics over time using OPM-MEG across three visits: baseline, 2 years, and 5 years. No results have yet been reported.

What this does not proveThe study has not yet posted results, meaning that planned endpoints and enrolment details cannot provide insights into outcomes or efficacy.
View trial record on ClinicalTrials.govNCT07689682AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyObservationalTrial registry record – peer review not applicable

Observational Study of Biomarkers in Multiple Sclerosis Patients

The study enrolled 200 adult patients with clinical presentations related to multiple sclerosis (MS), including CIS, RRMS, or progressive MS. It planned to assess changes in specific biomarkers over various follow-up periods but has not yet reported any findings.

What this does not proveNo results are available as of now, and the planned endpoints do not demonstrate any actual findings. This means the study's impact is currently unknown.
View trial record on ClinicalTrials.govNCT04860947AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyPhase 1/2Trial registry record – peer review not applicable

Safety Evaluation of CTX112 in Adults with Neurological Autoimmune Disorders

A Phase 1/2 interventional study involving 220 adults with various neurological autoimmune disorders, including progressive MS, was planned to evaluate the safety of CTX112. Participants were to be followed from the infusion up to 24 months, but no results have been posted yet.

What this does not proveNo results are posted, and planned enrollment and endpoints do not indicate outcomes or findings of the study.
View trial record on ClinicalTrials.govNCT07804004AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyObservationalTrial registry record – peer review not applicable

Hand Grip Strength in People with MS

An observational study with 300 people with MS is set to investigate how routine clinical parameters correlate with weekly working hours while measuring hand grip strength.

What this does not proveCurrently, there are no results reported as the study has not progressed past the planning stages.
View trial record on ClinicalTrials.govNCT07889271AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyInterventionalTrial registry record – peer review not applicable

Interventional Study of Virtual Reality Stimulation in People with Multiple Sclerosis

An interventional study was planned to enroll 30 participants aged 18 to 65 with Multiple Sclerosis. The study design included two groups receiving either Virtual Reality Gamma Sensory Stimulation or a Sham version, with the primary outcome measuring changes in fatigue impact (MFIS) over a follow-up period.

What this does not proveNo results are posted; planned enrollment and endpoints do not constitute findings.
View trial record on ClinicalTrials.govNCT07310862AI summary of a trial registry record. Not medical advice.
AI CuratorAI-generated
Research summary ·
AI summary · not yet reviewedHuman studyPhase 2/3Trial registry record – peer review not applicable

Phase 2/3 Study in Infants with Tuberous Sclerosis Complex

An interventional study planned to enroll 60 infants with Tuberous Sclerosis Complex (TSC) to evaluate vigabatrin and rapamycin against placebo, focusing on seizures and tumor volume over 730 days. No results have been posted, and primary endpoints include seizure occurrence and tumor measurements.

What this does not proveNo results are posted, and endpoints do not provide findings.
View trial record on ClinicalTrials.govNCT04987463AI summary of a trial registry record. Not medical advice.

Research summaries are for information, not medical advice. Always consult your MS team before changing treatment.